Allergy medicine for children

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Last updated date: 02.09.2025.

Allergy medicine for kids includes the drops this girl is being given to soothe her eyes – she’s tipping her head back to help

The right allergy medicine could transform your child’s daily life and their future health. Antihistamines and corticosteroids are common types of short-term symptom relief. Allergy immunotherapy may also be an option. This treatment aims to retrain kids’ bodies to be more tolerant of whatever triggers their allergic reactions.1

Rewinding for a moment, managing children’s allergies typically starts with helping them avoid their problem substance or allergen. After that, the treatment options vary from child to child, depending partly on their age and allergy. Topical remedies, like creams and eye drops, might work best for your little one. Or they may need oral allergy medication to relieve their symptoms. Having emergency treatment to hand is vital for children at risk of the most severe type of allergic reaction.2

You don’t have to be super-mom or dad and find the right allergy medicine all by yourself. Your doctor will suggest a treatment plan,2 if your child needs one. To find out more about retraining the immune system, ask them about allergy immunotherapy.

Is allergy medicine for kids different?

Kids may take the same type of drug as their allergic parents (allergies can run in families1). But the dose is likely to be lower and the instructions may be different for different age groups.3 There’ll be a minimum age too. Giving a child an adult dose of medication may have the wrong effect.3

The way to help your child is with the right medication designed for them, whether they’re an infant, toddler or at school. 

Pharmacist explaining to a mother and her young daughter when and how to take her allergy relief medication

Over-the-counter vs prescription medication

An over-the-counter (OTC) drug is one that is judged to be safe, effective and simple to use without prescription from a doctor. Some common medications for kids’ allergy symptoms, including certain antihistamines and corticosteroids, are available OTC. But allergy is complex and different children experience it differently. Some need stronger medication that only a doctor can prescribe.

Making an appointment with your GP will help your child get the most appropriate treatment, which may change as they get older. Allergy testing may be necessary if you don’t have a diagnosis yet.1  There could also be reasons to avoid a certain drug if your child has another condition and maybe takes medication already.3

The treatment journey for kids

Tackling airborne allergies early and keeping them under control may reduce the risk of kids developing asthma symptoms later.4 Avoiding their allergy trigger won’t always be possible but short-term relief like antihistamines or corticosteroids may still be enough to manage their symptoms. If not, allergy immunotherapy could be a long-term option to reduce those symptoms.

Let’s take a closer look at how the different medicines fit into this typical treatment journey.

Topical symptom relief for kids

Your child could have seasonal allergies to pollen or mold. Or indoor allergies to pet dander, dust mites, mold (again) or something else entirely. Symptom-relieving medicines tackle what’s going on inside them when they react to their trigger. Corticosteroids are anti-inflammatory and reduce swelling.5 Antihistamines and mast cell stabilizers6,7 block the histamine causing lots of their symptoms. If it’s mainly one part of their body that’s affected, then topical remedies could be the right choice.

Some medications are approved for infants and toddlers, others only from a certain age. Talk to your doctor and always read the information leaflet very carefully.

For a blocked, stuffy or itchy nose

There are corticosteroid nasal sprays8 and antihistamine nasal sprays for kids.9 You can also get combined antihistamine and steroid nasal sprays.10 Children can use decongestants but, like grown-ups, not for more than a few days.11 Mast cell stabilizers also come in a nasal spray.12 

Infographic about antihistamine, a common allergy medicine for kids for short-term relief. Details of the infographic listed below

Maybe you already use a saline nasal spray when your child gets a cold and has a blocked nose. It helps loosen and thin mucus and is even suitable for infants.13  Saline nasal sprays also seem to make corticosteroid nasal sprays work better by helping to clear the nose of mucus and reducing swelling.13 The same is true of oral antihistamines (more below) used to control allergic rhinitis, which children may also need to use less combined with a saline nasal spray.13

Your child may be anxious about nasal sprays at first so tell them exactly what’s going to happen.

For teary red eyes

There are different options here too, such as antihistamine or6 mast cell stabilizer eye drops,6 or a combination medication.6 You may need to treat your child’s eyes several times a day.14 Saline eyedrops or artificial tears can also soothe watery eyes.

Younger children may be even less keen about eyedrops than nasal sprays. You might need to offer them a small reward. Lean your child back and ask them to look up. Hold their top eyelid open and gently pinch the lower one to make a little pocket to catch the liquid.7

For sore itchy skin

Corticosteroid creams, gels, ointments and lotions are common treatments to soothe atopic dermatitis (eczema) and insect stings.5,15 They calm inflammation and itching and range from mild to very potent.16 There are non-steroid creams for treating children’s eczema too now.17 Ask your GP about them.

It’s important to improve skin barrier health too. An emollient will do that, as well as soothe your child’s soreness or itching.18

For asthma symptoms

Breathing in tiny environmental allergens can make children wheeze and cough. They may get short of breath and feel as if their chest is tight. Treatment depends on the severity of the symptoms but tends to involve different types of inhaler, one to control symptoms and another for sudden and potentially serious flare-ups.19 Corticosteroids are common daily treatment for kids, sometimes in combination inhalers.19 Beta-2 antagonists like salbutamol can offer quick relief.19

Infographic about corticosteroids, a common allergy medicine for kids for short-term relief. Details of the infographic listed below

Oral allergy medicine

Oral antihistamines can help with sneezing, coughing, a runny nose and other signs of hay fever in allergy season.20 They can also calm insect stings15 and hives21 and milder reactions to food.22 Depending how old your child is, they may be able to have capsules, tablets (some of them chewable), liquid or syrup. An ordinary teaspoon won’t deliver an accurate dose, so use the syringe or measuring spoon or cup that comes with the medication. Most oral antihistamines take 30 minutes or so to work.22 

Ask your GP about this option if topical medicine isn’t working. Or if your child has a wider range of allergy symptoms. Corticosteroid tablets are less commonly given to children, as they can cause growth problems if taken for a long time.23

Leukotriene modifiers counteract another chemical the body releases as a part of an allergic reaction.24 They may be a back-up to a corticosteroid inhaler if children are struggling with lower respiratory symptoms.24 Infants can have the granules from 6 months old.25 There are tablets for older kids. Leukotriene modifiers can help older children with allergic rhinitis (hay fever) too.26

Infographic about allergy immunotherapy, an allergy medicine for kids for long-term relief. Details of the infographic listed below

Allergy immunotherapy

Your child has allergic reactions because their immune system thinks a harmless substance is the enemy.1 Allergy immunotherapy (AIT) aims to change that.1 Repeated tiny doses of the trigger can help their body learn to tolerate contact with it.1 Think of it as retraining or rebooting their immune system.1

Immunotherapy is available for kids with allergies including to dust mites and some pollen. They need to be old enough to describe clearly any adverse reaction to the treatment. So it’s not usually given under 5 years of age.27 

Other types of immunotherapy may also be recommended for children at risk of severe systemic allergic reactions to insect venom1 or peanut.1

What does a course of AIT involve?27

Allergy immunotherapy can be given as tablets that quickly dissolve under the tongue or drops (SLIT) or as injections under the skin (SCIT). It depends on the type of allergy and the child’s age. Treatment time is 3 to 5 years.

  • Immunotherapy tablets (SLIT) are taken daily, the first dose under medical supervision in the doctor's office and after that at home.
  • Immunotherapy shots (SCIT) are always given at the doctor's office. This will be once or twice a week during the build-up phase as the amount of allergen gradually increases. When your child reaches the maintenance dose, injections are more spaced out.

Treatment time is 3 to 5 years but a child’s body may begin to get used to the allergen within a few months of starting immunotherapy.27 You could find they already need less short-term allergy medication.27 

Does allergy medicine for children have side effects?

Most medications can have unwanted effects in some people under certain circumstances. It’s the same for children’s allergy medicines. The information leaflet will list potential side effects so that you know what to look out for.  

You may have heard about older types of antihistamine causing sleepiness.28 These also carry a higher risk of adverse reactions in kids.28 So non-drowsy second-generation antihistamines are preferred now.

Your GP can guide you through this.

Emergency treatment for severe allergic reactions in kids

Some allergies may put a child at greater risk of anaphylaxis, which is a severe systemic allergic reaction. These include food, insect venom and latex (for instance in baby teats and dummies, balloons or sneakers29), as well as antibiotics and other medicines.2 

Anaphylaxis can happen suddenly and may be life-threatening so needs immediate medical attention.2 Your doctor may prescribe adrenaline in a nasal spray or auto-injector in case your child comes into contact with their trigger by accident.2

Infographic about adrenaline nasal sprays and auto-injectors, which are emergency allergy medicine for kids. Details of the infographic listed below

Ideally, your child should carry two adrenaline devices with them at all times as one dose may not be enough.2 And kids must still go to hospital even if the injection makes them feel better. This is in case of a secondary delayed anaphylactic reaction.2

Managing allergies and allergy medicines at school

Starting school can be an even bigger step for children with allergies. And for anxious parents. Your preparation starts well before their first day. If the school doesn’t ask about allergies, get in touch to explain and share your child’s allergy or asthma action plan. You’ll need to update this at the start of each year as medications and dosages can change.

You may have to fill in a form or write a letter of permission for the school to dispense or administer any allergy medications you take in for them. That could be symptom relief for year-round or seasonal allergies or treatments for use in an emergency. It is very important your little one knows how to get help quickly if they need adrenaline or a quick-relief inhaler in case of an asthma attack. 

Kids lined up in a school corridor with their teacher – the three behind are leaning out to smile at us past the boy in front

We all want our kids to become happily and safely independent. At some point they will manage and carry their own allergy medicine, when they’re ready. This is something to discuss with your GP or allergist. 

The short version

Allergy medicine for kids may be the same drug as for adults but the dosage might be lower and instructions different. Effective treatments will depend on your child’s age, trigger and the severity of their symptoms. Options range from short-term symptom relief to allergy immunotherapy, which aims to retrain their immune system. Managing allergies at school can be a big step. Seek medical help and talk to the school so your child can have the allergy medications they need when they need them. 

References

1. British Society for Immunology. Allergy briefing. Geraadpleegd 6 augustus 2025.
https://www.immunology.org/policy-and-public-affairs/briefings-and-position-statements/allergy

2. Muraro A, et al. EAACI guidelines: Anaphylaxis (2021 update). Allergy. 2022;77:357–377.
https://doi.org/10.1111/all.15032

3. Toni E, et al. Risk Factors Associated With Drug-Related Side Effects in Children: A Scoping Review. Glob Pediatr Health. 2024;11:2333794X241273171.
https://journals.sagepub.com/doi/10.1177/2333794X241273171

4. Burgess JA, et al. Childhood allergic rhinitis predicts asthma incidence and persistence to middle age: a longitudinal study. J Allergy Clin Immunol. 2007;120(4):863-869.
https://pubmed.ncbi.nlm.nih.gov/17825896/

5. NHS. Steroids. Geraadpleegd 6 augustus 2025.
https://www.nhs.uk/medicines/steroids/

6. Castillo M, et al. Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis. Cochrane Database of Systematic Reviews. 2015;6:CD009566.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10616535/

7. Nankervis H, et al. Scoping systematic review of treatments for eczema. Southampton (UK): NIHR Journals Library; 2016.
https://www.ncbi.nlm.nih.gov/books/NBK363127/

8. National Institute for Health and Care Excellence (NICE). Allergic rhinitis: Intranasal corticosteroids. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/intranasal-corticosteroids/

9. National Institute for Health and Care Excellence (NICE). Allergic rhinitis: Intranasal antihistamines. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/intranasal-antihistamines/

10. National Institute for Health and Care Excellence (NICE). Allergic rhinitis: Combined intranasal corticosteroid and antihistamine sprays. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/combined-intranasal-corticosteroid-antihistamine-sprays/

11. National Institute for Health and Care Excellence (NICE). Allergic rhinitis: Intranasal decongestants. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/intranasal-decongestants/

12. Minutello K, Gupta V. Cromolyn Sodium. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Geraadpleegd 7 augustus 2025.
https://www.ncbi.nlm.nih.gov/books/NBK557473/

13. Rhinology Online. The role of saline nasal sprays or drops in nasal hygiene: a review of the evidence and clinical perspectives*. Geraadpleegd 7 augustus 2025.
https://www.rhinologyonline.org/Rhinology_online_issues/manuscript_102.pdf

14. National Institute for Health and Care Excellence (NICE). Conjunctivitis - allergic:Topical ocular antihistamines and mast cell stabilizers. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/conjunctivitis-allergic/prescribing-information/topical-ocular-antihistamines-mast-cell-stabilizers/

15. National Institute for Health and Care Excellence (NICE). Insect bites and stings. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/insect-bites-stings/

16. National Institute for Health and Care Excellence (NICE). Eczema - atopic: Topical corticosteroids. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/eczema-atopic/prescribing-information/topical-corticosteroids/

17. National Institute for Health and Care Excellence (NICE). Eczema - atopic: Topical calcineurin inhibitors. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/eczema-atopic/prescribing-information/topical-calcineurin-inhibitors/

18. Elias PM. Optimizing emollient therapy for skin barrier repair in atopic dermatitis. Ann Allergy Asthma Immunol. 2022;128(5):505-511.
https://www.annallergy.org/article/S1081-1206(22)00015-1/fulltext

19. Royal United Hospitals Bath, NHS Foundation Trust. Asthma in Children and Young People. Geraadpleegd 22 augustus 2025.
https://www.ruh.nhs.uk/patients/patient_information/PAE023_Asthma_Information_and_management_plan.pdf

20. National Institute for Health and Care Excellence (NICE). Allergic rhinitis:Oral antihistamines. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/oral-antihistamines/

21. National Institute for Health and Care Excellence (NICE). Urticaria: Non-sedating antihistamines. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/urticaria/prescribing-information/non-sedating-antihistamines/

22. Park JH, et al. Comparison of cetirizine and diphenhydramine in the treatment of acute food-induced allergic reactions. J Allergy Clin Immunol. 2011;128(5):1127-1128.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205335/

23. National Institute for Health and Care Excellence (NICE). Corticosteroids – oral: Scenario: Corticosteroids. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/corticosteroids-oral/management/corticosteroids/

24. Sampson A, Holgate S. Leukotriene modifiers in the treatment of asthma. Look promising across the board of asthma severity. BMJ. 1998;316(7140):1257-1258.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1113026/

25. NHS. How and when to take Montelukast. Geraadpleegd 7 augustus 2025.
https://www.nhs.uk/medicines/montelukast/how-and-when-to-take-montelukast/

26. National Institute for Health and Care Excellence (NICE). Allergic rhinitis:Oral leukotriene receptor antagonists. Geraadpleegd 7 augustus 2025.
https://cks.nice.org.uk/topics/allergic-rhinitis/prescribing-information/oral-leukotriene-receptor-antagonists/

27. Alvaro-Lozano M, et al. Allergen Immunotherapy in Children User’s Guide. Pediatr Allergy Immunol. 2020;31(Suppl. 25):1-101.
https://onlinelibrary.wiley.com/doi/epdf/10.1111/pai.13189

28. Church DS, Church MK. Pharmacology of Antihistamines. World Allergy Organ J. 2011;4(Suppl 3):S22–S27.
https://waojournal.biomedcentral.com/articles/10.1186/1939-4551-4-S3-S22

29. Anaphylaxis UK. Latex allergy. Geraadpleegd 7 augustus 2025.
https://www.anaphylaxis.org.uk/fact-sheet/latex-allergy/

GB-NPR-2500024 Sep. 2025

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