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For most people insect stings and bites are a nuisance and nothing more. But swelling that spreads beyond the usual sore red bump could be a symptom of allergy. Insect stings can also cause a life-threatening allergic reaction called anaphylaxis so it’s important to know what to do and to do it fast.1
If you do have this allergy, it’s natural to be wary whenever you hear buzzing. Insect stings are the second most common cause of anaphylaxis in the UK outside medical settings, according to the National Institute for Health and Care Excellence (NICE).2
In this article we’ll talk about the insects that most commonly cause allergic reactions, how and why the allergy develops insect allergy, and what the symptoms are. Discover what to do if you are stung depending how severely you react. The article also talks about whether you can stop the allergic reactions after getting your diagnosis. And there are practical tips on how to avoid your trigger insect.
Insect allergy refers to allergic reactions to insect stings mainly in the Hymenoptera order. In the UK, this includes bees, wasps and hornets.3 Insect allergy can also be triggered by insect bites from certain mosquitoes, bed bugs, fleas, flies,4 ants3 and ticks.5
Ticks are technically not insects. They're arachnids like spiders and dust mites.6 But because they bite they're often grouped together with biting insects causing allergies. That's why we're talking about them here.
If you’re allergic to insect venom or saliva your immune system makes Immunoglobulin E (IgE) antibodies to combat the toxin. But you usually need to be stung or bitten at least twice before you develop allergy symptoms. The first time your body prepares its defenses by creating the antibodies. The next time you get bitten or stung, those specific IgE antibodies might trigger a reaction. That causes insect allergy symptoms.
Pain, redness and slight puffiness less than 10cm in diameter around the sting site are quite normal. With insect allergy, local symptoms tend to be more intense. More importantly, being stung can cause a sudden severe allergic reaction called anaphylaxis, which is a medical emergency.
Normal (non-allergic) reactions last a few hours and may not need treatment, while large local reactions can take days to subside.
With allergy, the reaction can be a similar size (10cm) to a normal sting but may be more swollen, painful, itchy and red.1 (On darker skin, the redness or erythema may be harder to see8). A large local reaction spreads further than this and could even make your arm or leg swell up. If you’re stung on your face or neck, the swelling could affect your breathing, in which case dial 999. 1
Depending on the severity, local allergic reactions often respond to the same remedies as a normal insect sting.1
Most sudden severe allergic reactions to insect stings develop within 30 minutes1 but it might be several hours later.9 The symptoms could affect any part of your body9 and this is what to look out for:
Sudden severe allergic reactions to insect stings are less common in kids until they reach school age (which is also when there’s a rise in the overall number of child anaphylaxis cases outdoors).11 Children are about half as likely to experience insect sting anaphylaxis than adults.12
It’s important to say that the UK has one of the lowest fatality rates in Europe from insect sting anaphylaxis. And it’s men who are at highest risk.12
Mild to moderate allergic reactions usually respond to basic first aid and symptom relief medication. First remove all traces of the insect. If a bee has left its stinger behind, gently scrape it sideways with a fingernail. Don’t pinch it or you may squeeze more venom under the skin.1
Ticks latch on to your skin. Use tweezers or a tick remover to grab the tick as close to your skin as you can. Pull it away without squeezing. Make sure you get the mouth parts out cleanly. Wash the bite with soap and water.13
Holding a cold compress or ice pack on the bit for 20 minutes may help to ease pain and reduce swelling.13 If it’s still uncomfortable, ask your pharmacist about short-term relief options:
An unusually large or painful local reaction may need medical attention and a prescription.1,13
Life-threatening allergic reactions can happen fast and need fast treatment. So your GP may prescribe adrenaline in a nasal spray or auto-injector for you to use in a medical emergency. Carry two devices with you at all times because a single dose may not be enough to reverse the reaction.
You may want to carry a medical ID or wear a medical alert bracelet. This lets others know you’re allergic to insect stings and may need immediate treatment if stung. It’s a good idea to teach your family and friends how to use your adrenaline device too, in case you can’t.
It isn’t a replacement for medical attention. Call an ambulance even if you start to feel better in case you have a delayed secondary reaction.
Your GP will take your medical history and a detailed account of your worst symptoms after a sting. Having a systemic reaction once makes it more likely to happen again.1 They will also ask if you know what type of insect stung you. Try to note:
Some insect venoms, like wasp and hornet, contain similar allergenic proteins. This causes cross-reactions and you may get allergy symptoms from more than just your trigger. Skin testing or blood tests can help make the diagnosis.3
Venom immunotherapy can reduce the risk of severe insect allergy symptoms. The treatment is also known as desensitization and it involves regular tiny doses of your particular insect allergen. The idea is to retrain your immune system so that it reacts differently. A full course takes 3 to 5 years.1,3
Treatment with one form of venom immunotherapy may address allergies to different insects. For example, wasp venom immunotherapy can tackle allergic reactions to hornets too. It’s because of the cross-reactivity we talked about before.
Insect venom immunotherapy is available for adults and children, depending on eligibility. Your GP or allergy specialist will assess and advise you.
Insect sting allergy is generally not a year-round problem unless you live somewhere tropical. The risk of is highest in the summer as life moves outdoors and you have more skin exposed. Insect repellents may not work on stinging insects so why not try these tips instead:
Insect allergies happen when the immune system overreacts to stings or bites.7 Problem insects include bees, wasps and hornets, and sometimes mosquitos and horse flies.1,4 The swelling, redness and itching will be more intense if you have an allergy, and it could spread beyond the normal 10cms in diameter. The most severe allergic reaction is called anaphylaxis, which can be life-threatening.1
An insect allergy diagnosis relies on looking at your medical history and the results of skin or blood tests.3 If the doctor thinks you’re at risk of anaphylaxis, they’ll ask you to carry two adrenaline nasal sprays or auto-injectors for emergencies. Venom immunotherapy can reduce the risk of anaphylaxis; ask your doctor if you could be eligible for treatment.1
If you’ve read all the way to the end of this article about stinging insect allergy, thank you. We’d love to know what you think. Have you tried any of the tips we’ve suggested? Or do you have any of your own that you’d like to share with others? We’re on Facebook and Instagram. Follow us there or email and share your story.
Klarify takes allergy science and makes it simple, and we have rigorous process for doing this. We use up-to-date and authoritative sources of information. Medical experts review our content before we share it with you. They and the klarify editorial team strive to be accurate, thorough, clear and objective at all times. Our editorial policy explains exactly how we do this.
1. Allergy UK. Your quick guide to allergy to bee and wasp stings. Geraadpleegd 12 augustus 2025.
https://www.allergyuk.org/wp-content/uploads/2022/02/Allergy-to-Wasp-Bee-Stings.pdf
2. National Institute for Health and Care Excellence (NICE). How common are insect bites and stings? Geraadpleegd 12 augustus 2025.
https://cks.nice.org.uk/topics/insect-bites-stings/background-information/prevalence/
3. Krishna MT, et al. Diagnosis and management of hymenoptera venom allergy: British Society for Allergy and Clinical Immunology (BSACI) guidelines. Clin Exp Allergy. 2011;41(9):1201-1220.
https://www.bsaci.org/wp-content/uploads/2021/02/j.1365-2222.2011.03788.x.pdf
4. Hemmer W, Wantke F. Insect hypersensitivity beyond bee and wasp venom allergy. Allergol Select. 2020;4:97–104.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7709451/
5. Burke G, et al. Hypersensitivity to Ticks and Lyme Disease Risk. Emerging Infectious Diseases. 2005;11(1):36-41.
https://wwwnc.cdc.gov/eid/article/11/1/04-0303_article#
6. Britannica. Arachnid. Geraadpleegd 12 augustus 2025.
https://www.britannica.com/animal/arachnid
7. British Society for Immunology. Allergy briefing. Geraadpleegd 9 april 2025.
https://www.immunology.org/policy-and-public-affairs/briefings-and-position-statements/allergy
8. British Association of Dermatologists. Skin diversity descriptors guidance for general public document. Geraadpleegd 13 augustus 2025.
https://cdn.bad.org.uk/uploads/2024/07/17092814/Skin-diversity-descriptors-guidance-General-Public-July.pdf
9. World Allergy Organization. Anaphylaxis guidance 2020. Geraadpleegd 13 augustus 2025.
https://www.worldallergyorganizationjournal.org/article/S1939-4551(20)30375-6/fulltext#secsectitle0025
10. Resuscitation Council UK. Emergency treatment of anaphylaxis: Guidelines for healthcare providers. Geraadpleegd 13 augustus 2025.
https://www.resus.org.uk/sites/default/files/2021-05/Emergency%20Treatment%20of%20Anaphylaxis%20May%202021_0.pdf
11. Grabenhenrich LB, et al. Anaphylaxis in children and adolescents: The European Anaphylaxis Registry. J Allergy Clin Immunol. 2016;137(4):1128-1137.e1.
https://www.jacionline.org/article/S0091-6749(15)02991-7/pdf
12. Feás X, et al. What We Know about Sting-Related Deaths? Human Fatalities Caused by Hornet, Wasp and Bee Stings in Europe (1994-2016). Biology (Basel). 2022;11(2):282.
https://www.mdpi.com/2079-7737/11/2/282
13. NHS. Insect bites and stings: Treatment. Geraadpleegd 13 augustus 2025.
https://www.nhs.uk/conditions/insect-bites-and-stings/
GB-NPR-2500022 Sep. 2025